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Similarity Searching & Homology Tools
Here the user will be able to use various sequence database similarity search tools such as Fasta, Blast, MPsrch and Scanps. Interactive as well as email submissions are available for each of these services
 

Fasta EBI (Protein)

                     

  

FASTA (pronounced FAST-Aye) stands for FAST-All, reflecting the fact that it can be used for a fast protein comparison or a fast nucleotide comparison.

 Tutorial

Fasta EBI (Nucleotide)

Tutorial

Specialised Fasta (EBI) 

       

Fasta-ASD server, Fasta-LGIC Protein server, Fasta-LGIC Nucleotide server,Fasta-Proteome server, Fasta-Genome server, Fasta-SNP server, Fasta-WGS server 

Paracel's Fast Data Finder (FDF)

At EMBnet-CH  

BLAST Network Service (ExPASY) 

The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

BLAST 

At EMBnet-CH/SIB (Switzerland)

BLAST at NCBI

Protein-protein BLAST (blastp), Nucleotide-nucleotide BLAST (blastn), Quickly search for highly similar sequences (megablast)

      

Tutorial

Other Similarity Search Tools 

At ExPASY, EBI (MPsrch, SCANPS-Scan Protein Sequence)

 
 
Sequence Format Conversion and DNA -> Protein Tools

 ReadSeq

 Automatically detects input format and converts into FASTA, Stanford, Genbank, NBRF, EMBL, GCG, DNAStrider, Fitch, Phylip, raw, PIR, MSF or NEXUS sequence formats

 SeqVerter

 Converts sequence between different formats

Translate

Translates a nucleotide sequence to a protein sequence

Transeq

Nucleotide to protein translation from the EMBOSS package

Backtranslation

 Translates a protein sequence back to a nucleotide sequence  

 DNA mutation Checker (EBI)

 A tool to verify the transcription and translation effects of DNA level sequence variation.

 Genewise

 Compares a protein sequence to a genomic DNA sequence

 
 
Sequence Assembly Tools

 ESSEM

Est aSSEmbly tool using Malig. On-line sequential web application is accessible. Allows the reconstruction of DNA sequences from a set of fragments.

Merger

Merge two overlapping nucleic acid sequences

CAP3

Contig Assembly Program Based on Sensitive Detection of Fragment Overlaps

 
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